刘晨光

发布者:杨光发布时间:2020-03-13浏览次数:4778

 

  

姓名:刘晨光

学历/职称/职务:

博士研究生/教授(博导)/副院长

联系方式:科学馆105

邮箱:liucg@ouc.edu.cn电话:0532-82032102

地址:山东青岛市鱼山路5

工作照:

学习工作简历:

1.学习简历
1986,9-1990,7曲阜师范大学生物学系获学士学位
   1992,9-1995,7
四川大学生物学系获硕士学位
   2002,12~2005,8 
高丽大学(韩国生命科学与技术学院获博士学位

2.工作简历
1995,9~1996,12 中国海洋大学助教
   1997,1~2002,12
中国海洋大学讲师
   1999,9~2000,2 
南京大学生物化学系国内访问学者

2003,1~2007,12 中国海洋大学副教授
   2008,1~
至今中国海洋大学教授(20087月获博士生导师资格)

2010,4~至今国家海洋生命科学与技术人才培养基地副主任

2013,6~至今海洋生命学院副院长

科研领域描述:

1)海洋生物技术

是指运用海洋生物学与工程学的原理和方法,利用海洋生物或生物代谢过程生产有用的生物制品。该研究方向主要进行海洋生物材料(如多糖、蛋白质(酶)、脂质)的分离、纯化、改性、鉴定及相关应用基础研究,已成功地分离纯化了多种新型的海洋多糖、海洋生物酶等。

2)微/纳米生物材料

是指用于对生物体进行诊断、治疗、修复或替换其病损组织、器官或增进其功能的具有微纳米结构或微纳米尺度的新型生物材料,已成功地制备了壳聚糖、海藻酸、透明质酸、浒苔多糖、海蜇胶原、氧化石墨烯等多种微/纳米材料。

以上研究成果在医药、食品和化妆品等领域显示出良好的应用前景,其中海洋生物化妆品已实现产业化并成功推向了市场。

研究兴趣:

1、微/纳米医用生物材料(药物缓释载体);

2、可食性微/纳米材料在功能性食品中的应用(营养物运送系统);

3、微/纳米生物技术在化妆品方面的应用(活性物质载体);

4、微生物胞外产物的分离、鉴定及应用;

5、基于适配体的药物递送及生物传感

代表性成果

Publications

2020

1.Zhang Pei, Guo Huixia and Liu Chenguang   Fabrication of Carboxylmethyl Chitosan Nanocarrier via Self-Assembly for   Efficient Delivery of Phenylethyl Resorcinol in B16 Cells. Polymers 2020, 12,   408; doi:10.3390/polym12020408

2019

1.Kazharska M, Ding Y, Arif M, Jiang F, Cong Y,   Wang H, Zhao C, Liu X, Chi Z, Liu C. Cellulose nanocrystals derived from   Enteromorpha prolifera and their use in developing bionanocomposite films   with water-soluble polysaccharides extracted from E. prolifera. International   Journal of Biological Macromolecules 2019 134:390-396

2.Luan L., Chi, Z.; Liu, C. Chinese White Wax   Solid Lipid Nanoparticles as a Novel Nanocarrier of Curcumin for Inhibiting   the Formation of Staphylococcus aureus Biofilms Nanomaterials (Basel). 2019   May; 9(5): 763. 10.3390/nano9050763

3. Zhang P., Zhao S., Yu Y. , Wang H., Yang Y.,   Liu C. Biocompatibility Profile and In Vitro Cellular Uptake of   Self-assembled Alginate Nanoparticles Molecules 2019, 24, 555;   doi:10.3390/molecules 24030555

4. Li Q., Xue F., Qu J. Liu L., Hu R., Liu C.   Nano-in-Micro Delivery System Prepared by Co-Axial Air Flow for Oral Delivery   of Conjugated Linoleic Acid Mar. Drugs 2019, 17, 15; doi:10.3390/md 17010015

5. Cong Y., Geng J., Wang H., Su J., ArifM, Dong Q. Chi, Z.; Liu, C. Liu Ureido-modified   carboxymethyl chitosan-graft-stearic acid polymeric nano-micelles as a   targeted delivering carrier of clarithromycin for Helicobacter pylori:   Preparation and in vitro evaluation International Journal of Biological   Macromolecules 2019 129:686-692

6.LI   Jiaxin, ZHANG Pei, HONG Liang, and LIU Chenguang Purification and   Characterization of a Novel Hydrolase That Can Specifically Degrade the   Polysaccharide Isolated from Green Seaweed Ulva prolifera J. Ocean Univ.   China (Oceanic and Coastal Sea Research) 2019 18 (1): 185-192

2018

1. Arif, M.; Raja, M. Ali; Zeenat, S.; Chi, Z.;   Liu, C. Development of novel pH-sensitive thiolated chitosan/PMLA   nanoparticles for amoxicillin delivery to treat Helicobacter pylori Materials   Science & Engineering C 2018 83: 17–24

2. Sun Q.; Luan L.; Arif M. Li J,; Chi Z.; Liu C.   Redox-sensitive nanoparticles based on 4-aminothiophenol-carboxymethyl inulin   conjugate for budesonide delivery in inflammatory bowel diseases Carbohydrate   Polymers 218 189 352–359

3.Li J, Jiang, F., Chi, Z, Han D, Yu L, Liu C.   Development of Enteromorpha prolifera polysaccharide-based   nanoparticles for delivery of curcumin to cancer cells International Journal   of Biological Macromolecules 2018 112:413-421

4. Li CB, Liu CG Characterization of Agarose   Microparticles Prepared by Water-in-water Emulsification. Particulate Science   and Technology 2018 36: 592-599

  

2017

1. Li Q., Hong L., Li HG *, Liu CG *. Graphene   oxide-fullerene C60 (GO-C60) hybrid for photodynamic and photothermal therapy   triggered by near-infrared light. Biosensors and Bioelectronics, 2017: 89   477–482

2. Raja MA, Arif M, Feng C, Zeenat S, Liu CG.   Synthesis and evaluation of pH-sensitive, self-assembled chitosan-based   nanoparticles as efficient doxorubicin carriers. Journal of Biomaterials Applications.   2017 311182-1195.

3.Arif M, Raja MA, Zeenat S, Chi Z, Liu CG.   Preparation and characterization of polyelectrolyte complex nanoparticles   based on poly (malic acid), chitosan. A pH-dependent delivery system. Journal   of Biomaterials Science, Polymer Edition. 2017: 28 50-62..

4. Cheng X, Shao Z, Li C, Yu L, Raja MA, Liu CG.   Isolation, Characterization and Evaluation of Collagen from Jellyfish   Rhopilema esculentum Kishinouye for Use in Hemostatic Applications. PloS one.   2017 Jan 19; 12(1):e0169731.

5. Hong L., Chen F, Han D, Wang, C., Li, J., Chi,   Z., Liu, C. Development of a carboxymethyl chitosan functionalized   nanoemulsion formulation for increasing aqueous solubility, stability and   skin permeability of astaxanthin using low-energy method Journal of   Microencapsulation 2017 34: 707-721

6. Hong L., Han D., Li MX, Zhang P., Liu CG   Development and validation of an Ultraviolet–visible (UV-Vis)   spectrophotometric method for determination of phenylethyl resorcinol in new   topical nanoemulsions, International Journal of Cosmetic Science, 2017: 39   337–343

7. Li JX, Chi Z., Yu LJ, Jiang F, Liu CG Sulfated   modification, characterization, and antioxidant and   moistureabsorption/retention activities of a soluble neutral   polysaccharidefrom Enteromorpha prolifera International Journal of Biological   Macromolecules 2017 105:1544-1553

  

2016

1. Raja MA   Zeenat S Arif M. Liu CG * Self-assembled nanoparticles based on amphiphilic   chitosan derivative and arginine for oral curcumin delivery International   Journal of Nanomedicine 2016:11 4397–4412

2. Wang S,   Zheng L, Cui ZS, Chen JH, Yang BJ, Han XT, Liu CG Cloning and molecular   characterization of a delta-6 fatty acid desaturase gene from Isochrysis sp.   CCMM5001 J Appl Phycol 2016 28:921–929

  

2015

1. Zhang P,   Zhao SR, Li JX, Hong L, Raja MA, Yu LJ, Liu CG* Nanoparticles based on   phenylalanine ethyl ester-alginate conjugate as vitamin B-2 delivery system   Journal of Biomaterials Applications 2016, 31: 13-227.Yulong Tan, Su Ma,   Chenguang Liu, Wengong Yu, Feng Han* Enhancing the stability and antibiofilm   activity of DspB byimmobilization on carboxymethyl chitosan nanoparticles   Microbiological Research 2015 178: 35–41

2.Li, Q.,   Liu, C.-G*., Yu, Y.Separation of monodisperse alginate nanoparticles   and effect of particle size on transport of vitamin ECarbohydrate Polymers2015 124: 274-279

3.Wen-Hao   Wei, Xue-Meng Dong and Chen-Guang Liu* In Vitro Investigation of   Self-Assembled Nanoparticles Based on Hyaluronic Acid-Deoxycholic Acid   Conjugates for Controlled Release Doxorubicin: Effect of Degree of   Substitution of Deoxycholic Acid Int. J. Mol. Sci. 2015, 16: 7195-7209

4.Mazhar   Ali Raja, Chenguang Liu* and Zhenhua Huang Nanoparticles based on Oleate   Alginate Ester as Curcumin Delivery System Current Drug Delivery, 2015, 12:   613-627 613

  

2013

1. Li,   Qian; Yu, Yu; Liu, Chenguang* Preparation and evaluation of nanoparticles   with narrow size distribution for oral delivery J. Control. Release 2013, 172   DI:10.1016/j.jconrel

2012

2.Wu JL,   Liu CG, Wang XL, Huang ZH. Preparation and characterization of nanoparticles   based on histidine-hyaluronic acid conjugates as doxorubicin carriers. J   Mater Sci Mater Med. 2012, 23:1921-1929.

3.iShiqi;   Zhao Rui; Yin Qi; Liu Chenguang; Zhang Xiaohua Gel microbead cultivation with   a subenrichment procedure can yield better bacterial cultivability from a   seawater sample than standard plating method JOURNAL OF OCEAN UNIVERSITY OF   CHINA 2012 11 45-51

2011

1.Qian Li,   Chen-Guang Liu,* Zhen-Hua Huang, and Fang-Fang Xue Preparation and Characterization   of Nanoparticles Based on Hydrophobic Alginate Derivative as Carriers for   Sustained Release of Vitamin D3J.   Agric. Food Chem.;2011, 59, 1962–1967

2010

1. Xuemeng   Dong, Chenguang Liu* Preparation and Characterization of Self-Assembled   Nanoparticles of Hyaluronic Acid-Deoxycholic Acid Conjugates. Journal of   Nanomaterials 2010, doi:10.1155/2010/906936

2009

1.Yu-long   Tan, Chen-Guang Liu Self-aggregated nanoparticles from linoleic acid modified   carboxymethyl chitosan: Synthesis, characterization and application in vitro   Colloids and Surfaces B: Biointerfaces 2009 69 178–182

2008

1.Yu-long   Tan, Chen-Guang Liu Xi-Guang Chen Effect of linoleic-acid modified   carboxymethyl chitosan on bromelain immobilization onto self-assembled   nanoparticles 2008 Frontiers of Materials Science in China 2(2)209-213

2006

1.Chen, Xi   GuangCheng   Sheng; Liu, Chen Guang Preparation and biocompatibility of chitosan   microcarriers as biomaterial BIOCHEMICAL ENGINEERING JOURNAL 2006 27 269-274

2005

1.   K.G.H.Desai, C. Liu and H.J. Park Characteristics of vitamin C immobilized   particles and sodium alginate beads containing immobilized particles J.   Microencapulation 2005; 22(4); 363-376

2. Liu,   C.-G.; Desai, K. G. H.; Chen, X.-G.; Park, H.-J. Preparation and   characterization of nanoparticles containing trypsin based on hydrophobically   chitosan J. Agric. Food Chem.; 2005, 53, 1728-1733

3.   Chen-Guang Liu, Xi-Guang Chen, Hyun-Jin Park Self-assembled nanoparticles   based on linoleic-acid modified chitosan: Stability and adsorption of trypsin   Carbohydrate Polymers 2005 62 293–298

  

获奖:

1)2008年入选教育部新世纪优秀人才支持计划

2)教育部自然科学奖二等奖(2010年,第4位)

3)海洋科学技术奖二等奖(2013年,第3位)