张晓娜

发布者:杨光发布时间:2020-03-03浏览次数:2461


姓名:张晓娜

学历/职称:博士/副教授/硕士生导师

邮箱:zxn_xiaona@ouc.edu.cn     电话13969777433

地址:青岛市鱼山路5号,中国海洋大学海洋生命学院,生态馆203

学习/工作经历

2005/09--2009/06,中国海洋大学,生态学专业,生态学学士学位

2009/09--2014/06,中国海洋大学,生态学专业,硕博连读,生态学博士学位

2014/07--2015/08,中国海洋大学 海洋生命学院 科研博后

2015/09--2018/12,中国海洋大学 海洋生命学院 讲师

2019/01至今,中国海洋大学 海洋生命学院 副教授

研究方向

目前主要从事生态毒理学研究,研究方向包括:(1) 环境污染物对鱼类的内分泌干扰效应及危害机制;(2) 以斑马鱼为模式生物探究新型有机污染物的环境健康效应及致病机制;(3) 新型有机污染物对贝类的危害机制和健康风险评估研究。

 主持国家自然科学基金青年基金1项(21707129),中国海洋大学青年教师科研专项基金1项,作为课题骨干参与国家重点研发计划1项,主持并参与多项横向课题。

代表性论文(*通讯作者)

1. Wang Weiwei, Zhang Xiaona*, Qin Jingyu, Jia Yi, Wang Jun, Ru Shaoguo*. Long-term bisphenol S exposure induces fat accumulation in liver ofadult male zebrafish (Danio rerio) and slows yolk lipid consumption inF1 offspring. Chemosphere, 2019,221: 500510. (SCI二区, IF=5.108)

2. Zhao Dan,Zhang Xiaona*, Liu Dasheng, Ru Shaoguo*. Cu accumulation, detoxification and tolerance in the red swamp crayfish procambarus clarkii. Ecotoxicology and Environmental Safety, 2019, 175, 201-207. (SCI二区, IF=4.527)

3. Zhao Dan,Zhang Xiaona*, Li Xuefu, Ru Shaoguo, Wang Yanwen, Yin Jinbin, Liu Dasheng*. Oxidative damage induced by copper in testis of the red swamp crayfish Procambarus clarkii and its underlying mechanisms. Aquatic toxicology, 2019, 207, 120–131. (SCI, IF=3.794)

4. Wei Penghao, ZhaoFei, ZhangXiaona*, LiuWenmin, JiangGuobin, WangHongfang, RuShaoguo. Transgenerational thyroid endocrine disruption induced by bisphenol S affects the early development of zebrafish offspring. Environmental Pollution, 2018 243: 800808. (SCI二区, IF=5.714)

5. Wang Weiwei, Zhang Xiaona*, Wang Zihao, Qin Jingyu, Wang Wei, Tian Hua, Ru Shaoguo*. Bisphenol S induces obesogenic effects through deregulating lipid metabolism in zebrafish (Danio rerio) larvae. Chemosphere, 2018 199: 286–296. (SCI二区, IF=5.108)

6. Zhang Xiaona, Liu Wei, Wang Jun, Tian Hua, Wang Wei, Ru Shaoguo. Quantitative analysis of in-vivo responses of reproductive and thyroid endpoints in male goldfish exposed to monocrotophos pesticide. Comparative Biochemistry and Physiology Part C, 2018 211: 4147. (SCI三区, IF = 2.426)

7. Zhang Xiaona1, Xu Lei1, Tian Hua, Wang Cuicui Wang Wei, Ru Shaoguo*. Monocrotophos, an organophosphorus insecticide, disrupts the expression of HpNetrin and its receptor neogenin during early development in the sea urchin (Hemicentrotus pulcherrimus). NeuroToxicology, 2017, 62: 130–137. (SCI二区, IF=3.10)

8. Zhang Xiaona, Li Shuman, Wang Cuicui, Tian Hua, Wang Wei, Ru Shaoguo*. Effects of monocrotophos pesticide on cholinergic and dopaminergic neurotransmitter systems during early development in the sea urchin Hemicentrotus pulcherrimus. Toxicology and Applied Pharmacology, 2017 328: 46–53. (SCI二区, IF=3.791)

9. Dong Yifei, Zhang Xiaona*, Tian Hua, Li Xiang, Wang Wei, Ru Shaoguo*. Effects of polychlorinated biphenyls on metamorphosis of a marine fish Japanese flounder (Paralichthys olivaceus) in relation to thyroid disruption. Marine Pollution Bulletin, 2017, 119: 325–331. (SCI一区, IF=3.145)

10. Zhang Xiaona, Zhong Yan, Tian Hua, Wang Wei, Ru Shaoguo*. Impairment of the cortisol stress response mediated by the hypothalamus-pituitary-interrenal (HPI) axis in zebrafish (Danio rerio) exposed to monocrotophos pesticide. Comparative Biochemistry and Physiology Part C, 2015, 176–177: 10–16. (SCI三区, IF = 2.546)

11. Zhang Xiaona, Tian Hua, Wang Wei, Ru Shaoguo*. Monocrotophos pesticide decreases the plasma levels of total 3,3′,5-triiodo-L-thyronine and alters the expression of genes associated with the thyroidal axis in female goldfish (Carassius auratus). Plos one, 2014, 9 (9) :e108972 (SCI三区, IF = 3.53)

12. Zhang Xiaona, Tian Hua, Wang Wei, Ru Shaoguo*. Exposure to monocrotophos pesticide causes disruption of the hypothalamic–pituitary–thyroid axis in adult male goldfish (Carassius auratus). General and Comparative Endocrinology, 2013, 193: 158–166. (SCI三区, IF = 2.823)

13. Zhang Xiaona, Gao Lei, Yang Kunfeng, Tian Hua, Wang Wei, Ru Shaoguo*. Monocrotophos pesticide modulates the expression of sexual differentiation genes and causes phenotypic feminization in zebrafish (Danio rerio). Comparative Biochemistry and Physiology, Part C, 2013, 157: 33–40. (SCI三区, IF = 2.707)

14. Liu Wenmin, Zhang Xiaona, Wei Penghao, Tian Hua, Wang Wei, Ru Shaoguo*. Long-term exposure to bisphenol S damages the visual system and reduces the tracking capability of male zebrafish (Danio rerio). Journal of Applied Toxicology, 2018, 38(2): 248–258. (SCI三区, IF = 3.158)

15. Yu Miao, Zhang Xiaona, Guo Linlin, Tian Hua, Wang Wei, Ru Shaoguo*. Anti-estrogenic effect of semicarbazide in female zebrafish (Danio rerio) and its potential mechanisms. Aquatic Toxicology, 2016, 170: 262270. (SCI一区, IF=3.557)

16. Wang Zhenyu, Zhang Xiaona, Tian Hua, Wang Wei, Ru Shaoguo*. Effects of monocrotophos pesticide on steroidogenesis and transcription of steroidogenic enzymes in rainbow trout RTG-2 cells involving the protein kinase A signal pathway. Toxicology in vitro, 2015, 29:155–161. (SCI二区, IF =3.20)

17. GaoMing, Wang Jun, Zhang Xiaona, Dahlgren Randy A., Ru Shaoguo*, Wang Xuedong*. Integrated disperser freezing purification with extraction using fatty acidbased solidification of floating organic-droplet (IDFP-EFA-SFO) for triclosanand methyltriclosan determination in seawater, sediment and seafood. Marine Pollution Bulletin, 2018, 137: 677–687.(SCI一区, IF=3.241)

18. Yue Zonghao, Yu Miao, Zhang Xiaona, Dong Yifei, Tian Hua, Wang Wei, Ru Shaoguo*. Semicarbazide-induced thyroid disruption in Japanese flounder (Paralichthys olivaceus) and its potential mechanisms. Ecotoxicology and Environmental Safety, 2017, 140: 131140. (SCI二区, IF=3.13)

19. Yu Miao, Feng Yongliang, Zhang Xiaona, Wang Jun, Tian Hua, Wang Wei, Ru Shaoguo*. Semicarbazide disturbs the reproductive system of male zebrafish (Danio rerio) through the GABAergic system. Reproductive Toxicology, 2017, 73: 149157. (SCI, IF=2.341)

20. 刘文敏,张晓娜*魏朋浩,汝少国。双酚S长期暴露对雌性斑马鱼视觉系统的影响。中国海洋大学学报,201848(11)7178