张晓华

发布者:杨光发布时间:2024-10-10浏览次数:26375

张晓华博士、教授/博士生导师


个人简历

姓名:张晓华

学历/职称/职务:博士/二级教授/博士生导师

联系方式:

邮箱:xhzhang@ouc.edu.cn电话:0532-82032767 (办公室)

地址:青岛市鱼山路5号 青岛266003 中国海洋大学海洋生命学院

工作照:

学习工作简历:

1983.091987.07山东大学生物系动物学专业,获学士学位

1987.091990.07山东大学生物系动物生理专业,获硕士学位

1990.081994.10山东省海洋药物研究所,助理研究员

1994.101998.04青岛海洋大学海洋生命学院讲师、副教授(1997.12)

1998.042000.11英国赫里奥特-瓦特大学生物系微生物学专业,获博士学位

2000.122003.11英国牛津大学动物学系博士后

2003.112004.06英国剑桥大学遗传系博士后

2004.07至今:中国海洋大学海洋生命学院副教授、教授(2004.12)、博士生导师(2005.12)

三级教授(2013.1)、二级教授(2019.1

科研领域描述:

主要研究方向为微生物海洋学,重点关注海洋微生物驱动的生物地球化学循环机制,尤其是海洋微生物驱动的有机硫DMSP/DMS循环、碳循环机制。

主要研究课题:

2004.012006.12主持国家自然科学基金项目“海洋弧菌中溶血素的研究”(30371119),经费20万元。

2005.012007.12入选2004年教育部新世纪优秀人才支持计划(NCET-04-0645),经费50万元。

2007.122010.12主持国家863计划项目“中国黄海微生物资源采集、保存和信息化技术”(2007AA09Z434),经费100万元。

2008.012010.12主持国家自然科学基金项目“哈维氏弧菌VHH溶血素作用机理的研究”(30771656),经费32万元。

2008.012009.12主持教育部科学技术研究重点项目“致病性哈维氏弧菌毒性相关质粒的研究”(108082),经费10万元。

2009.012011.12主持国家自然科学基金项目“海洋拮抗菌假交替单胞菌JG1作用机理的研究”(40876067),经费44万元。

2009.012011.12主持国家自然科学基金委与香港研究资助局(NSFC-RGC)联合科研基金项目“弧菌毒力因子对鱼类细胞保护和细胞调亡的作用研究” (30831160512),内地经费31.5万元。

2008.122012.12国家 863计划重点项目“迟钝爱德华氏菌毒力相关功能基因研究及疫苗开发”(2008AA092501),参与,个人经费84万元。

2012.012015.12国家 863计划重点项目“深海微生物分离培养与基因资源获取技术研究”(2012AA092103)子课题“深海微生物高通量分离培养技术及装置研发”,主持,经费190万元。

2012.072014.06主持科技部国际科技合作重点项目“利用密度感应抑制技术控制水产养殖细菌性病害的合作研究”(2012DFG31990),经费100万元。

2013.012016.12主持国家自然科学基金项目“南太平洋环流区洋底沉积物及海水的微生物群落演化及功能活性研究”(41276141),经费87万元。

2013.012018.12国家自然科学基金创新群体项目“海洋有机生物地球化学”(41221004 &延续41521064),参加,个人经费34万元。

2013.012015.09中国大洋协会国际海域资源调查与开发“十二五”项目“深海结核、结壳区微生物多样性与资源潜力评价”(DY125-15-R-03),参加,个人经费104万元。

2015.012018.12主持国家自然科学基金项目“我国边缘海颗粒有机碳中细菌密度感应及其对有机碳降解的调控作用”(41476112),经费100万元。

2016.062021.05国家重点研发计划“全球变化及应对”重点专项“中国东部陆架海域生源活性气体的生物地球化学过程及气候效应”项目课题3“微生物在海洋生源活性气体循环中的作用与机制”(2016YFA0601303)。个人经费120万。

2018.012022.12主持国家自然科学基金重点项目“弧菌在我国边缘海的生态分布及在碳循环中的作用研究”(41730530)。经费376.4万元。

2018.012021.12主持国家自然科学基金委“水圈微生物驱动地球元素循环的机制”重大研究计划重点支持项目“海洋异养细菌对DMSP/DMS产生的贡献及驱动硫循环的机制:以马里亚纳海沟为例”(91751202)。经费382.3万元。

2018.012020.12青岛海洋科学与技术试点国家实验室山东省海洋科技资金重大科技专项“蓝色药库”技术创新工程项目“海洋药源生物基础研究”课题 6-4海洋细菌多样性、分子生态学及功能解析 (2018SDKJ0406-4),参加。个人经费60万元。

2018.052018.11广州海洋地质调查局地质调查项目“试采海底孔隙压力监测与海洋物理环境研究”(2018C-03-186),参加。个人经费32.2万元。

2019.07-2019.08科技部国际合作司发展中国家技术培训班“海洋微生物学技术国际培训班”(20190176)。经费:30.5648万元。

2020.012022.12主持国家重点研发计划政府间国际科技创新合作重点专项“以弧菌作为生物感应器指示全球/区域变化的研究”(2018YFE0124100)。经费288万元。

2021.04-2024.12主持中央高校基本科研业务费“深海化能生态系统的生命-环境协同演化及元素循环驱动机制”(202172002)。经费1160万元。

2023.01-2024.12主持国家自然科学基金委“水圈微生物驱动地球元素循环的机制”重大研究计划集成项目“深海微生物驱动的碳氮硫循环及相关储碳机制集成研究”(92251303)。直接经费1160万元。

2024.01-2027.12主持国家自然科学基金面上项目“深海放线菌新型DMSP裂解酶的鉴定及其生理生态功能研究”(32370118)。直接经费50万元.

获奖情况及荣誉称号:

1. 入选2004年教育部“新世纪优秀人才支持计划”。

2. 2010年国家海洋创新成果二等奖(第1位),获奖题目:哈维氏弧菌溶血素的发现与致病机理。

3. 2014年国家海洋科学技术二等奖(第1位),获奖题目:海洋微生物培养新技术的建立及菌种库建设。

4. 2014年青岛市自然科学二等奖(第1位),获奖题目:海水鱼类主要病原菌的致病性及其环境适应机制。

5. 2022年国家海洋科学技术二等奖(第1位),获奖题目:利用密度感应淬灭技术对水产养殖细菌性病害的控制研究。

6. 2023年山东省自然科学二等奖(第1位),获奖题目:深渊海购微生物驱动的生物地球化学循环及高压适应机制。

7.获 20142016201720192021山东省优秀硕士/博士学位论文指导教师。

8. 主讲的研究生课程《海洋微生物学》(Marine Microbiology),2021年获山东省研究生教育优质课程立项建设。

9. 主编的《海洋微生物学》(第二版,科学出版社)获2020年山东省普通高等教育一流教材。

10. 主讲的《海洋微生物学》课程2023年获第二批国家一流本科课程(线下课程)。

代表性论文

  1. Zhang Y, Sun C, Guo Z, Liu L, Zhang X, Sun K, Zheng Y, Gates AJ, Todd JD*Zhang X-H*. A S-methyltransferase producing the climate-active gas dimethylsulfide is widespread in marine bacteria and environments. Nat Microbiol, 2024, 9: 2614-2625.SCI, IF2023: 20.5

  2. Wang J, Curson ARJ, Zhou S, Carrión O, Liu J, Vieira A, Walsham KS, Monaco S, Li C-Y, Dong Q-Y, Wang Y, Rivera PPL, Wang X-D, Zhang M, Hanwell L, Wallace M, Zhu X-Y, Leão PN, Lea-Smith DJ, Zhang Y-Z, Zhang X-H*, Todd JD*. Alternative dimethylsulfoniopropionate biosynthesis enzymes in diverse and abundant microorganisms. Nat Microbiol, 2024, 9: 1979-1992.IF2023: 20.5

  3. Zhang Y, Liu J, Song D, Yao P, Zhu S, Zhou Y, Jin J, Zhang X-H*. Stochasticity-driven weekly fluctuations distinguished the temporal pattern of particle-associated microorganisms from its free-living counterparts in temperate coastal seawater. Water Research, 2024, 248: 120849.

  4. Liu J, Li D W, He X, Liu R, Cheng H, Su C, Chen M, Wang Y, Zhao Z, Xu H, Cheng Z, Wang Z, Pedentchouk N, Lea Smith DJ, Todd JD, Liu X*, Zhao M*, Zhang X H*. A unique subseafloor microbiosphere in the Mariana Trench driven by episodic sedimentation. Mar Life Sci Tech, 2024, 6:168–181.SCI, IF2023: 6.0

  5. Cheng H, Zhang Y, Guo Z, He X, Liu R, Zhu X-Y, Li J, Liu J, Zhang X-H*. Microbial dimethylsulfoniopropionate cycling in deep sediment of the Mariana Trench. Appl Environ Microbiol, 2023, 89: 00251-23.SCI, IF2022: 4.4

  6.  Liu J, Huang F, Liu J, Liu X, Lin R, Zhong X, Austin B, Zhang X-H*. Phylotype resolved spatial variation and association patterns of planktonic Thaumarchaeota in eastern Chinese marginal seas. Mar Life Sci Tech, 2023, 5:257–270.SCI, IF2022: 5.7

  7. Chen X, J Liu J, Zhu X-Y, Xue C-X, Yao P, Fu L, Yang Z, Sun K, Yu M, Wang X, Zhang X-H*. Phylogenetically and metabolically diverse autotrophs in the world’s deepest blue hole. ISME Commun, 2023, 3: 117.SCI, IF2023: 5.1

  8. Liu J, Xue C-X, Wang J, Crombie AT, Carrión O, Johnston AWB, Murrell JC, Liu J, Zheng Y, Zhang X-H*, Todd JD*. Oceanospirillales containing the DMSP lyase DddD are key utilisers of carbon from DMSP in coastal seawater. Microbiome, 2022, 10:110.IF2021: 16.837

  9. Liang J, Liu J, Wang X, Sun H, Zhang Y, Ju F, Thompson F, Zhang X-H*. Genomic analysis reveals adaptation of Vibrio campbellii to the hadal ocean. Appl Environ Microbiol, 2022, 88: 00575-22.IF2021: 5.005

  10. Liu J, Qiao Y, Xin Y, Lin R, Zhang Y, Li Y, Yu M, Zhang X-H*. Seasonal succession and temperature response pattern of microbial community in the Yellow Sea Cold Water Mass. Appl Environ Microbiol, 2022, 88: 01169-22.IF2021: 5.005

  11. Wang X, Liu J, Zhao W, Liu J, Liang J, Thompson F, Zhang X-H*. Fine-scale structuring of planktonic Vibrio spp. in the Chinese marginal seas. Appl Environ Microbiol, 2022, 88: 01262-22.IF2021: 5.005

  12. He X, Zhang Y, Wang X, Zhu X, Chen L, Liu W, Lyu Q, Ran L, Cheng H, Zhang X-H*. Characterization of multiple alginate lyases in a highly efficient alginate-degrading Vibrio strain and its degradation strategy. Appl Environ Microbiol, 2022, 88: 01389-22.IF2021: 5.005

  13. Liang J, Liu J, Zhan Y, Zhou S, Xue C-X, Sun C, Lin Y, Luo C, Wang X, Zhang X-H*. Succession of marine bacteria in response to Ulva prolifera-derived dissolved organic matter. Environ Int, 2021, 155: 106687.IF2021: 13.352

  14. Sun H, Liu J, Tan S, Zheng Y, Wang X, Liang J, Todd JD*, Zhang X-H*. Spatiotemporal distribution of bacterial dimethylsulfoniopropionate producing and catabolic genes in the Changjiang Estuary. Environ Microbiol, 2021, 23:7073–7092.IF2021: 5.476

  15. Zheng Y, Wang J, Zhou S, Liu J, Xue C-X, Williams BT, Zhao X, Zhao L, Zhu X-Y, Sun C, Xiao T, Todd JD*, ZhangX-H*. Bacteria are important dimethylsulfoniopropionate producers in marine aphotic and high-pressure environments. Nat Commun, 2020, doi: 10.1038/s41467-020-18434-4 ((IF2020:14.919)

  16. Liu J, Zhu S, Liu X, Yao P, Ge T, Zhang X-H*. Spatiotemporal dynamics of the archaeal community in coastal sediments: assembly process and co-occurrence relationship. ISME J, 2020, doi: 10.1038/s41396-020-0621-7.SCI, IF2019: 9.180 )

  17. Zhong H, Lehtovirta-Morley L, Liu J, Zheng Y, Lin H, Song D, Todd JD, Tian J, Zhang X-H*. Novel insights into the Thaumarchaeota in the deepest oceans: their metabolism and potential adaptation mechanisms. Microbiome, 2020, 8:78.IF2019: 11.607

  18. Wang X, Liu J, Liang J, Sun H, Zhang X-H*. Spatiotemporal dynamics of the total and active Vibrio spp. populations throughout the Changjiang estuary in China. Environ Microbiol, 2020, 2020, 22: 4438–4455.IF2020: 5.491

  19. Xue C-X, Zhang H, Lin H-Y, Sun Y, Luo D, Huang Y, Zhang X-H*, Luo H*. Ancestral niche separation and evolutionary rate differentiation between sister marine flavobacteria lineages. Environ Microbiol, 2020, 22: 3234–3247.IF2020: 5.491

  20. Liu J, Zheng Y, Lin H, Wang X, Li M, Liu Y, Yu M, Zhao M, Pedentchouk N, Lea-Smith DJ, Todd JD, Magill CR, Zhang W-J, Zhou S, Song D, Zhong H, Xin Y, Yu M, Tian J*, Zhang X-H*. Proliferation of hydrocarbon degrading microbes at the bottom of the Mariana Trench. Microbiome, 2019, 7: 47.SCI, IF2018: 10.465

  21. Williams BT, Cowles K, Martínez AB, Curson ARJ, Zheng Y, Liu J, Newton-Payne S, Hind A, Li C-Y, Rivera PPL, Carrión O, Liu J, Spurgin LG, Brearley CA, Mackenzie BW, Pinchbeck BJ, Pratscher J, Zhang X-H, Zhang Y-Z, Murrell JC, Todd JD. Bacteria are important dimethylsulfoniopropionate producers in coastal sediments. Nat Microbiol, 2019, 4:1815–1825. (SCI, IF2017: 14.174)

  22. Liang J, Liu J, Wang X, Lin H, Liu J, Zhou S, Sun H, and Zhang X-H*. Spatiotemporal dynamics of free-living and particle-associated Vibrio communities in the northern Chinese marginal seas. Appl Environ Microbiol,  2019, 85:e00217-19.SCI, IF2018: 4.077

  23. Wang X, Liu J, Li B, Liang J, Sun H, Zhou S, and Zhang X-H*. Spatial heterogeneity of Vibrio spp. in sediments of Chinese marginal seas. Appl Environ Microbiol, 2019, 85:e03064-18.SCI, IF2018: 4.077

  24. Xu T, Yu M, Liu J, Lin H, Liang J, and Zhang X-H*. Role of RpoN from Labrenzia aggregate LZB033 (Rhodobacteraceae) in formation of flagella and biofilms, motility, and environmental adaptation. Appl Environ Microbiol, 2019, 85:e02844-18.SCI, IF2018: 4.077

  25. Zhang X-H*, Liu J, Liu J, Yang G-P, Xue C, Curson ARJ, Todd JD. Biogenic production of DMSP and its degradation to DMS– their roles in global sulfur cycle. Sci China Life Sci, 2019, 62, 1296–1319.SCI, IF2018: 3.583

  26. Zhang X-H*, Lin H, Wang X, Austin B. Significance of Vibrio species in the marine organic carbon cycle – a review. Sci China Earth Sci, 2018, 61(10): 1357-1368. (SCI, IF2018: 2.258;封面文章)

  27. Curson A, Liu J, Martinez AB, Green R, Chan Y, Carrion O, Williams B, Zhang S-H, Yang G-P, Page PB, Zhang X-H* & Todd J*. 2017. Dimethylsulphoniopropionate biosynthesis in marine bacteria and identification of the key gene in this process. Nat Microbiol, 2017, 2: e17009. (SCI, IF2017: 14.174)

  28. D'Hondt S, Inagaki F, Zarikian C, Abrams L, Dubois N, Engelhardt T, Evans H, Ferdelman T, Gribsholt B, Harris R, Hoppie B, Hyun J-H, Kallmeyer J, Kim J, Lynch J, McKinley C, Mitsunobu S, Morono Y, Murray R, Pockalny R, Sauvage J, Shimono T, Shiraishi F, Smith D, Smith-Duque C, Spivack A, Steinsbu B, Suzuki Y, Szpak M, Toffin L, Uramoto G, Yamaguchi Y, Zhang G-L, Zhang X-H, and Ziebis W. 2015. Presence of oxygen and aerobic communities from seafloor to basement in deep-sea sediment. Nature Geoscience, 8(4), 299-304. (SCI, IF2015: 12.508)

  29. Tang K, Su Y, Brackman G, Cui F, Zhang Y, Shi X, Coenye T, Zhang X-H*. 2015. MomL, a novel marine-derived N-acyl homoserine lactonase from Muricauda olearia. Appl Environ Microbiol, 81:774 –782. (SCI, IF2015: 3.823)

  30. Fu B, Liu J, Yang H, Hsu TC, He B, Dai M, Kao SJ, Zhao M, Zhang X-H*. 2015. Shift of anammox bacterial community structure along the Pearl Estuary and the impact of environmental factors. J Geophys Res – Oceans, 120, 2869–2883. (SCI, IF2015: 3.318)



Curriculum Vitae

Name:Xiao-Hua Zhang

Title: Professor in Microbial Oceanography

Contact

Emailxhzhang@ouc.edu.cn              Tel0086-532-82032767 (office)

Address

Colleage of Marine Life Sciences

Ocean University of China

Yushan 5 Road, Qingdao 266003, China

Photo

Experiences:

Education

4/1998-7/2001

PhD in Microbiology, Department of Biological Sciences, Heriot-Watt University, U.K.

9/1987-7/1990

MSc in Physiology, Biological Department, Shandong University, China

9/1983-7/1987

BSc. in Zoology, Biological Department, Shandong University, China

Employment and experience

07/2004-present

Professor in Marine Microbiology, Colleage of Marine Life Sciences, Ocean University of China, China

11/2003-06/2004


Postdoctoral Researcher in Department of Genetics, Cambridge University, U.K.

12/2000-10/2003

Postdoctoral Researcher in Department of Zoology, Oxford University, U.K.

8/1994-4/1998

Lecturer and Associate Professor in Marine Microbiology, Colleage of Marine Life Sciences, Ocean University of China, P.R. China

7/1990-8/1994

Research associate in Shandong Institute of Marine Materia Media, China

Teaching

Teaching Microbiology, Marine Microbiology and Biological Oceanography


Research Interests

 Microbial oceanography (including roles of marine microorganisms in driving biogeochemical cycles; bacterial quorum sensing and quorum quenching; marine bacterial taxonomy and   applications).