李红岩

发布者:张文博发布时间:2023-10-17浏览次数:17114

李红岩,博士,教授                  

邮箱:hongyanli@ouc.edu.cn

电话:0532-82032092

实验室网站:http://iemb.ouc.edu.cn/18973/list.htm

承担课程:细胞工程(本科生),发育生物学与细胞分化(研究生)


学习工作经历:

1993~1997 烟台大学,生物化学专业,获学士学位

1997~2002 青岛海洋大学,海洋生物学,获博士学位

2002~至今 中国海洋大学,讲师/副教授/教授/博导

2003~2007 法国巴黎第六大学,博士后


主要科研领域:

主要从事动物发育与进化生物学研究。研究聚焦于模式动物斑马鱼的组织器官形成,对发育过程中重要基因的功能、作用机制以及相关的信号通路进行研究。已在国际主流刊物发表论文50余篇,成果发表在Development, JBC, Mech. Dev.等国际权威期刊。主要承担国家自然科学基金面上项目及青年项目等多项课题;入选2011年教育部新世纪优秀人才计划。获国家海洋局海洋创新成果奖一等奖(第3位)及教育部自然科学奖二等奖(第4位)各一项。


代表性成果:(#共同第一;*通讯作者)

  1. Yang S#, Xu X#, Zhang A, Wang Y, Ji G, Sun C*, Li H*. The evolution and immunomodulatory role of Zc3h12 proteins in zebrafish (Danio rerio). Int J Biol Macromol. 2023; 39:124214.

  2. Li X, Guo R, Yang S, Zhang X, Yin X, Teng L, Zhang S, Ji G*, Li H*. Cd248a and Cd248b in zebrafish participate in innate immune responses. Front Immunol. 2022; 3:970626.

  3. Yang S, Zhang X, Li X, Yin X, Teng L, Ji G*, Li H*. Evolutionary and Expression Analysis of MOV10 and MOV10L1 Reveals Their Origin, Duplication and Divergence. Int J Mol Sci. 2022; 3(14):7523.

  4. Wang S, Ji D, Yang Q, Li M, Ma Z, Zhang S*, Li H*. NEFLb impairs early nervous system development via regulation of neuron apoptosis in zebrafish. J Cell Physiol. 2019, 234(7):11208-11218.

  5. Yang Q#, Wang P#, Yang S, Li X, Zhang X, Ji G, Zhang S, Wang S*, Li H*. A novel hepatic lectin of zebrafish Danio rerio is involved in innate immune defense. Fish Shellfish Immunol. 2020, 98: 670-680.  

  6. Wang X, Du X, Li H*, Zhang S*. Identification of the Zinc Finger Protein ZRANB2 as a Novel Maternal Lipopolysaccharide-binding Protein That Protects Embryos of Zebrafish against Gram-negative Bacterial Infections. J Biol Chem. 2016; 291(8):4019-34.

  7. Li HY, Grifone R, Saquet A, Carron C, Shi DL. The Xenopus homologue of Down syndrome critical region protein 6 drives dorsoanterior gene expression and embryonic axis formation by antagonising polycomb group proteins. Development. 2013, 140(24):4903-13.

  8. Yang Q, Wang P, Wang S, Wang Y, Feng S, Zhang S, Li H*. The hepatic lectin of zebrafish binds a wide range of bacteria and participates in immune defense. Fish Shellfish Immunol. 2018, 82: 267-278.

  9. Ji D, Wang S, Li M, Zhang S, Li H*. Involvement of Lypge in the formation of eye and pineal gland in zebrafish. Gene. 2018 Feb 5;642:491-497

  10. Wang M, Li L, Guo Q, Zhang S, Ji D*, Li H*. Identification and expression of a new Ly6 gene cluster in zebrafish Danio rerio, with implications of being involved in embryonic immunity. Fish Shellfish Immunol. 2016; 54:230-40.