臧晓南

发布者:杨光发布时间:2018-09-19浏览次数:8029


 

臧晓南  博士

职称:教授,硕士生导师

工作经历:

2005.7~至今  中国海洋大学海洋生命学院     生物工程系教师

研究方向:藻类遗传育种

从事藻类遗传学、种质改良及藻类高值化产品开发应用。主要研究藻类有光学活性藻胆蛋白的合成机制;重要产琼胶海藻龙须菜优良品系选育及抗逆机制研究;富含DHA裂壶藻的选育和DHA合成机制研究等。主持863计划课题、国家科技重大专项子任务、国家自然科学基金项目、山东省优秀中青年科学家科研奖励基金项目、教育部重点项目等9项,参与863计划项目、科技部农业科技成果转化资金项目等7项,已发表论文80余篇,其中以第一及通讯作者发表SCI论文21篇。

 

承担的主要课题:

主持国家自然科学基金项目藻胆蛋白复合体的异源合成组装及其结构和功能的研究(31872555(第一)

主持国家自然科学基金项目基于龙须菜色素突变体的有光学活性藻红蛋白的生物合成机制研究(31472255”(第一)

主持国家自然科学基金项目“龙须菜高温胁迫响应基因的克隆、鉴定与表达模式分析(30700608)” (第一)

主持国家863计划课题“裂殖壶菌OUC88发酵技术研究及工业化应用(2008AA09Z410)”(第一)

主持国家转基因生物新品种培育重大专项“高产转基因水稻新品种培育(2008ZX08001-0042011ZX08001-0042013ZX08001-004)”子任务“水稻捕光功能的分子改良研究”

主持教育部博士点基金新教师项目“龙须菜耐高温性状的QTL定位研究20070423011)”(第一)

主持教育部重点项目“鲆鲽鱼类生长激素基因克隆及其体外表达研究(108083)”(第一)

主持山东省优秀中青年科学家科研奖励基金(博士基金)“碳源对DHA在裂殖壶菌中累积作用研究及工业化应用  (BS2012HZ017)” (第一)

主持新奥集团横向课题“裂殖壶菌发酵优化及遗传转化体系的构建(20120644)”(第一)

 

主要论文:

1、  Bangxiang He, Lulu Hou, Xiaonan Zang *, Xuecheng Zhang, Jiawei Shi, Xiaoyun Huang, Yating Ding, Manman Dong, Xiaomei Cong, Feng Zhang.Transcriptome Analysis in Haematococcus pluvialis: Astaxanthin Induction by high light with acetate and Fe2+.  International Journal of molecular sciences. Int. J. Mol. Sci. 2018, 19, 175; doi:10.3390/ijms19010175SCI收录, IF: 3.687

2、  Yuming Jin. Xiaonan Zang*. Xiaoyun Huang. Xuexue Cao. Deguang Sun. Jiaojiao Lin. Zhu Liu. Chang Liu. Yalin Guo. Zhendong Wang. Lulu Hou. Cloning of ho Gene from Gracilariopsis lemaneiformis and Study on Its Function on the Expression of a Fluorescent Phycoerythrobilin in Heterologous Hosts. Journal of Applied Phycology. 2018. DOI: 10.1007/s10811-018-1464-8 SCI收录, IF: 2.401

3、   Liu Yuantao, Sun Hengyi, Ding Yan, Zang Xiaonan*, Zhang Xuecheng. A novel heat shock protein from Gracilaria lemaneiformis: Gene cloning and transcription analysis in response to heat stress. Journal of Applied Phycology. 2018. DOI: 10.1007/s10811-018-1494-2 SCI收录, IF: 2.401

4、  Yating Ding, Zang Xiaonan*, Jiawei Shi, Lulu Hou, Bangxiang He, Manman Dong, Xuexue Cao, Zhu Liu, Xiaomei Cong, Xinwei Song, Xiaoyun Huang, Xuecheng Zhang. Cloning, Transcription and Enzyme Activity Analysis of gs, gogat and gdh Genes of Haematococcus pluvialis in Different Nitrogen Concentration. Journal of Applied Phycology. 2018. DOI: 10.1007/s10811-018-1564-5.SCI收录, IF: 2.401

5、  Xiaoyun Huang, Xiaonan Zang*, Fei Wu, Yuming Jin, Haitao Wang, Chang Liu, Yating Ding, Bangxiang He, Dongfang Xiao, Xinwei Song, Zhu Liu. Transcriptome Sequencing of Gracilariopsis lemaneiformis to Analyze the Genes Related to Optically Active Phycoerythrin Synthesis. Plos One. DOI:10.1371/journal.pone.0170855 January 30, 2017 SCI收录, IF: 3.057

6、  Lu-lu Hou, Feng Liu, Xiaonan Zang, Xuecheng Zhang, Bangxiang He, Yating Ding, Xinwei Song, Dongfang Xiao, Haitao Wang. Cloning and transcription analysis of the nitrate reductase gene from Haematococcus pluvialis. Biotechnol Lett. 2017, 39:589–597. DOI 10.1007/s10529-016-2283-0 SCI收录, IF: 1.639

7、  Liu Yuantao, Zhang xuan, Sun Hengyi, Yang Qin, Zang Xiaonan*, Zhang Xuecheng, Tan Yanmiao. Cloning and transcription analysis of six members of the calmodulin family in Gracilaria lemaneiformis under heat shock. Journal of Applied Phycology. 2016, 28: 643-651. DOI: 10.1007/s10811-015-0575-8. SCI收录, IF: 2.616

8、  Fei Wu, Xiaonan Zang*, Xuecheng Zhang, Ran Zhang, Xiaoyun Huang, Lulu Hou, Minjie Jiang, Chang Liu and Chunhong Pang. Molecular Cloning of cpcU and Heterodimeric Bilin Lyase Activity Analysis of CpcU and CpcS for Attachment of Phycocyanobilin to Cys-82 on the Subunit of Phycocyanin in Arthrospira platensis FACHB314. Molecules 2016, 21, 357; doi:10.3390/molecules21030357SCI收录, IF: 2.416

9、  Le Gong; Meijuan Gao; Xiaonan Zang*; Xuan Zhang; Xuecheng Zhang Peptidase: a novel member of a Calmodulin-binding protein of Gracilaria lemaneiformis under heat shock. Journal of Applied Phycology. 2015. 27(1): 563-570. DOI: 10.1007/s10811-014-0280-zSCI收录, IF: 2.559

10、              Yan Ding, Hengyi Sun, Ran Zhang, Qin Yang, Yuantao Liu, Xiaonan Zang* , Xuecheng Zhang. Selection of reference gene from Gracilaria lemaneiformis under temperature stress. Journal of Applied Phycology.2015, 27(3): 1365-1372. DOI: 10.1007/s10811-014-0423-2SCI收录, IF: 2.559

11、              Hengyi Sun, Hao Chen, Xiaonan Zang*, Pan Hou, Bingbing Zhou, Yuantao Liu, Fei Wu, Xiaofei Cao, Xuecheng Zhang. Application of the Cre/loxP site-specific recombination system for gene transformation in Aurantiochytrium limacinum. Molecules. 2015, 20, 10110-10121. doi:10.3390/molecules200610110SCI收录, IF: 2.416

12、              Hengyi Sun, Xiaonan Zang*, Yuantao Liu, Bingbing Zhou, Feng Liu, Fei Wu, Xiaoyun Huang , Minjie Jiang, Xuecheng Zhang. Expression of chimeric human/salmon calcitonin gene integrated by rDNA in Saccharomyces cerevisiae. Applied Microbiology and Biotechnology. 2015, 99: 10097-10106. DOI: 10.1007/s00253-015-6834-4.SCI收录, IF: 3.337

13、              Xuan Zhang; Huiyue Zhou; Xiaonan Zang*; Le Gong; Hengyi Sun; Xuecheng Zhang. MIPS: a Calmodulin binding protein of Gracilaria lemaneiformis under heat shock. Marine Biotechnology. 2014. 16:475-483. DOI: 10.1007/s10126-014-9565-0. 2014 SCI收录, IF: 3.269

14、              Guang-Qi Li, Xiao-Nan Zang*, Xue-Cheng Zhang, Ning Lu, Yan Ding, Le Gong and Wen-Chao Chen. Ubiquitin-Activating Enzyme and Ubiquitin-Conjugating Enzyme Genes Cloned from Gracilaria lemaneiformis and active under Heat Shock. Gene. 2014, 5381): 155-163. DOI: 10.1016/j.gene.2013.12.017  (SCI收录, IF: 2.138)

15、              Ran Zhang, Xiao-Ting Feng, Fei Wu, Yan Ding, Xiao-Nan Zang*, Xue-Cheng Zhang, Ding-Yang Yuan, Bing-Ran Zhao. Molecular cloning and expression analysis of a new bilin lyase: the cpcT gene encoding a bilin lyase responsible for attachment of  phycocyanobilin to Cys-153 on the β-subunit of phycocyanin in Arthrospira platensis FACHB314. Gene. 2014, 544(2): 191-197.  http://dx.doi.org/10.1016/j.gene.2014.04.050 (SCI收录, IF: 2.138)

16、              Ning Lu, Yan Ding, Xiaonan Zang*, Xuecheng Zhang, Hao Chen and Xiaosheng Mu. Molecular cloning and expression analysis of glutathione peroxidase and glutathione reductase from Gracilaria Lemaneiformis under heat stress. Journal of Applied Phycology. 2013.25(6):1925-1931. DOI: 10.1007/s10811-013-0020-9SCI收录, IF: 2.411

17、              Ning Lu, Xiaonan Zang*, Xuecheng Zhang, Hao Chen, Xiaoting Feng and Lu Zhang. 2012, Gene Cloning, Expression and Activity Analysis of Manganese Superoxide Dismutase from Two Strains of Gracilaria lemaneiformis (Gracilariaceae, Rhodophyta) under Heat Stress. Molecules 2012, 17,4522-4532; doi:10.3390/molecules17044522 SCI收录, IF: 2.386

18、              Yinghui Gu, Xuan Zhang, Ning Lu, Xiaonan Zang*,Xuecheng Zhang, Guangqi Li. Cloning and transcription analysis of hsp70-1 and hsp70-2 of Gracilaria lemaneiformis under heat shock. Aquaculture. 2012358-359 284-291. doi: 10.1016/j.aquaculture.2012.05.040 SCI收录, IF: 2.041

 

主要专利

1、    臧晓南,张学成,陈浩,孙恒一,徐涤。中华人民共和国专利: 一种无抗生素标记的裂殖壶菌及其遗传转化方法. 已授权. 专利号:201410502278.9.

2、    张学成, 宋晓金, 臧晓南. 中华人民共和国专利: 一种裂殖壶菌的发酵生产工艺. 已授权. 专利号: 201010104774.0.

3、    张学成, 刘滨, 臧晓南, 刘顺梅. 中华人民共和国专利: 转牙鲆生长激素基因酵母及其制备方法和应用. 已授权. 专利号: 200810109081.3.

4、    张学成, 王玉梅, 周一江, 臧晓南. 中华人民共和国专利: 融合蛋白及其制备方法. 已授权. 专利号: 200410075843.4.

5、    张学成,陈伟洲,臧晓南,徐涤。龙须菜“2007经国家水产原种和良种申定委员会审定,获得《水产新品种证书》(GS-01-011-2013)。

 

主要奖励

参与完成的科研项目“螺旋藻/节旋藻的基础研究、养殖和开发应用”获2004年度教育部科技进步一等奖。(第十)

参与完成的科研项目“龙须菜新品系选育技术研究与栽培示范”获2012年度汕头市科学技术奖励一等奖。(第三)

指导学生完成的硕士论文“高温胁迫下龙须菜抗氧化系统的研究”被评为2013山东省优秀硕士学位论文