刘光磊

发布者:张文博发布时间:2023-10-17浏览次数:24290

刘光磊,博士,教授

邮箱:liugl@ouc.edu.cn


承担课程:

《微生物学》,《合成生物学》


学习工作经历:

 2004~2008,中国海洋大学海洋生命学院,学士,生物科学专业

2008~2012,中国海洋大学海洋生命学院,博士,微生物学专业

 2012~2013,中国科学院青岛生物能源与过程研究所,助理研究员

 2013~2020,中国海洋大学海洋生命学院,讲师/副教授

2021至今,中国海洋大学海洋生命学院,教授


主要科研领域:

主要从事海洋酵母菌的研究。本团队近年来致力于酵母菌碳代谢及产物合成中的关键蛋白功能、途径解析和重构以及调控机制。已在国内外主流刊物发表论文上30余篇,成果发表在Mol Microbiol, Carbohydr Polym, J Agric Food Chem, Food Chem等国际权威期刊上,授权发明专利4项,并获山东省自然科学二等奖(第三位)。主持承担了国家自然基金面上项目(2项)、国家自然基金青年基金项目、山东省自然科学基金重大基础研究项目、山东省重点研发计划和企业横向等项目课题,并获得山东优青项目支持。


代表性成果:(#共同第一;*通讯作者)

  1. Liu, G. L. #; Bu, X. Y. #; Chen, C.; Fu, C.; Chi, Z.; Kosugi, A.; Cui, Q.; Chi, Z. M.; Liu, Y. J., Bioconversion of non-food corn biomass to polyol esters of fatty acid and single-cell oils. Biotechnol Biofuels Bioprod 2023, 16 (1), 9.

  2.  Li, F.; Wang, M.; Chi, Z.; Zhang, Z.; Wang, X.; Xing, M.; Chi, Z.; Liu, G. *, A novel transcriptional activation mechanism of inulinase gene in Kluyveromyces marxianus involving a glycolysis regulator KmGcr1p with unique and functional Q-rich repeats. Mol Microbiol 2022, 117 (5), 1063-1079.

  3.  Zhu, Y. #; Han, Y. #; Liu, G. #; Bian, Z.; Yan, X.; Li, Y.; Long, H.; Yu, G.; Wang, Y., Novel indole-mediated potassium ion import system confers a survival advantage to the Xanthomonadaceae family. ISME J 2022.

  4.  Xing, M.; Wang, Y.; Zhao, Y.; Chi, Z.; Chi, Z.; Liu, G. *, C-Terminal bacterial immunoglobulin-like domain of kappa-carrageenase serves as a multifunctional module to promote kappa-carrageenan hydrolysis. J Agric Food Chem. 2022, 70 (4), 1212-1222.

  5.  Wei, X. #; Liu, G. L. #; Jia, S. L.; Chi, Z.; Hu, Z.; Chi, Z. M., Pullulan biosynthesis and its regulation in Aureobasidium spp. Carbohydr Polym. 2021, 251, 117076.

  6. Liu, G. #; Zhao, X. #; Chen, C.; Chi, Z.; Zhang, Y.; Cui, Q.; Chi, Z.; Liu, Y. J., Robust production of pigment-free pullulan from lignocellulosic hydrolysate by a new fungus co-utilizing glucose and xylose. Carbohydr Polym 2020, 241, 116400.

  7.  Mao, W.; Han, Y.; Wang, X.; Zhao, X.; Chi, Z.; Chi, Z.; Liu, G. *, A new engineered endo-inulinase with improved activity and thermostability: Application in the production of prebiotic fructo-oligosaccharides from inulin. Food Chem 2019, 294, 293-301

  8.  Wang, M.; Mao, W.; Wang, X.; Li, F.; Wang, J.; Chi, Z.; Chi, Z.; Liu, G. *, Efficient simultaneous production of extracellular polyol esters of fatty acids and intracellular lipids from inulin by a deep-sea yeast Rhodotorula paludigena P4R5. Microb Cell Fact 2019, 18 (1), 149.

  9.  Han, Y. Z.; Zhou, C. C.; Xu, Y. Y.; Yao, J. X.; Chi, Z.; Chi, Z. M.; Liu, G. L. *, High-efficient production of fructo-oligosaccharides from inulin by a two-stage bioprocess using an engineered Yarrowia lipolytica strain. Carbohydr Polym 2017, 173, 592-599.

  10. Liu, G. L.; Chi, Z.; Wang, G. Y.; Wang, Z. P.; Li, Y.; Chi, Z. M., Yeast killer toxins, molecular mechanisms of their action and their applications. Crit Rev Biotechnol 2015, 35 (2), 222-34.