秦贞奎

发布者:张文博发布时间:2023-10-17浏览次数:11292

秦贞奎,博士,副教授

邮箱:qinzk@ouc.edu.cn

电话:0532-82032780


承担课程:

本科生课程《发育生物学》,《发育生物学实验》

研究生课程《发育生物学与细胞分化》


学习工作经历:

2004.09~2008.06,中国海洋大学海洋生命学院,生物科学,学士

2008.09~2011.06,中国海洋大学海洋生命学院,海洋生物学,硕士

2011.08~2015.12Auburn University, School of Fisheries, Aquaculture and Aquatic Sciences, Fisheries and Allied Aquaculture, Ph.D.

2013.01~2015.05Auburn University, College of Sciences and Mathematics, Probability and Statistics, Master

2016.01~2017.12,中国海洋大学海洋生命学院,讲师

2018至今,中国海洋大学海洋生命学院,副教授


主要科研领域:

主要研究方向海洋动物生殖发育的分子机制,以贝虾等重要水产经济物种为研究对象,通过遗传发育等多种技术手段对其生殖发育的分子调控机制进行解析。

近年来已在国内外主流刊物发表论文50余篇,主要成果以第一或通讯作者发表在Nature Ecology & Evolution, Aquaculture, ACS Synthetic Biology, Frontiers in Marine Science等国际主流期刊上;授权国家发明专利及美国发明专利多项。

主持承担了国家自然科学基金面上项目、国家自然科学基金青年基金、山东省自然科学基金青年基金等项目;作为课题骨干参与国家重点研发计划、山东省自然科学基金重大基础研究项目,及其它市级校级项目等。


代表性成果:(#共同第一;*通讯作者)

1. Jing Wang#, Lingling Zhang#, Shanshan Lian#, ZhenkuiQin#, Xuan Zhu#, Xiaoting Dai, Zekun Huang, Caihuan Ke, Zunchun Zhou, Jiankai Wei, Pingping Liu, Naina Hu, Qifan Zeng, Bo Dong, Ying Dong, Dexu Kong, Zhifeng Zhang, Sinuo Liu, Yu Xia, Yangping Li, Liang Zhao, Qiang Xing, Xiaoting Huang, Xiaoli Hu, Zhenmin Bao, Shi Wang*. Evolutionary transcriptomics of metazoan biphasic life cycle supports a single intercalation origin of metazoan larvae. Nature Ecology & Evolution, 2020, 4: 725–736. (中科院小类一区TOPIF=15.461

2. Shutong Fan#, Xixi Li#, Xiaolin Guo, Ruiqi Zhang, Yue Chen, Feng Zhao, Lingling Zhang, Zhenkui Qin*, Zhifeng Zhang. Examination of the role of a novel transcription factor in activating Foxl2 and its potential involvement in the regulation of ovarian development in scallops. Aquaculture, 2023, 578, 740113.中科院小类一区TOPIF=4.500

3. De Xing, Mei Shang, Shangjia Li, Wenwen Wang, Tasnuba Hasin, Darshika Hettiarachchi, Veronica Alston, Logan Bern, Zhenkui Qin*, Baofeng Su*, Rex Dunham. CRISPR/Cas9-mediated precision integration of fat-1 and fat-2 from Caenorhabditis elegans at long repeated sequence in channel catfish (Ictalurus punctatus) and the impact on n-3 fatty acid level. Aquaculture, 2023, 567: 739229.中科院小类一区TOPIF=4.500

4. Xiaolin Guo, Xixi Li, Feng Zhao, Danwen Liu, Zujing Yang, Moli Li, Yajuan Li, Huilan Wei, Hao Wang, Zhenkui Qin*, Zhifeng Zhang, Zhenmin Bao. Full-length transcriptome analysis provides insights into larval shell formation in Mulinia lateralis. Frontiers in Marine Science, 2023, 9: 1111241.中科院小类一区TOPIF=3.700

5. De Xing, Shangjia Li, Mei Shang, Wenwen Wang, Qin Zhang, Jinhai Wang, Tasnuba Hasin, Darshika Hettiarachchi, Veronica Alston, Logan Bern, Abel Paladines Parrales, Cuiyu Lu, Michael Coogan, Andrew Johnson, Zhenkui Qin*, Baofeng Su*, Rex Dunham. A New Strategy for Increasing Knock-in Efficiency: Multiple Elongase and Desaturase Transgenes Knock-in by Targeting Long Repeated Sequences. ACS Synthetic Biology, 2022, 11: 4210-4219.中科院小类一区TOPIF=4.700

6. De Xing, Baofeng Su, Max Bangs, Shangjia Li, Jinhai Wang, Logan Bern, Rhoda Mae C Simora, Wenwen Wang, Xiaoli Ma, Michael Coogan, Andrew Johnson, Yi Wang, Zhenkui Qin*, Rex Dunham*. CRISPR/Cas9 - mediated knock-in method can improve the expression and effect of transgene in P1 generation of channel catfish (Ictalurus punctatus). Aquaculture, 2022, 560: 738531.中科院小类一区TOPIF=4.500

7. Xixi Li, Siyun Lin Shutong Fan, Xiaoting Wang, Zhifeng Zhang*,Zhenkui Qin*. Identification and Characterization of MicroRNAs Involving in Initial Sex Differentiation of Chlamys farreri Gonads. Biology-basel, 2022, 11, 456.IF=4.200

8. Shutong Fan, Xixi Li, Siyu Lin, Yunpeng Li, Huixin Ma, Zhifeng Zhang*,Zhenkui Qin*. Screening and Identification of Transcription Factors Potentially Regulating Foxl2 Expression in Chlamys farreri Ovary. Biology-basel, 2022, 11, 113.IF=4.200

9. De Xing, Baofeng Su, Shangjia Li, Max Bangs, David Creamer, Michael Coogan, Jinhai Wang, Rhoda Simora, Xiaoli Ma, Darshika Hettiarachchi, Veronica Alston, Wenwen Wang, Andrew Johnson, Cuiyu Lu, Tasnuba Hasin, Zhenkui Qin*, Rex Dunham*. CRISPR/Cas9 Mediated Transgenesis of the Masu Salmon (Oncorhynchus masou) elovl2 Gene Improves n 3 Fatty Acid Content in Channel Catfish (Ictalurus punctatus). Marine Biotechnology, 2022, 24: 513-523.中科院小类二区,IF=3.000

10. Maokai Wei, Zhenkui Qin, Dexu Kong, Danwen Liu, Qiaojun Zheng, Shumiao Bai, Zhifeng Zhang*, Yuben Ma*. Echiuran Hox genes provide new insights into the correspondence between Hox subcluster organization and collinearity pattern. Proceedings of the Royal Society B-Biological Sciences, 2022, 289: 20220705.Nature Index,中科院小类一区TOPIF=4.700