王慧贞 博士，副教授，硕士生导师
地址：青岛市市南区鱼山路5号中国海洋大学化学馆
学习工作经历
2010.09-2014.06，山东师范大学，生物科学，学士
2014.09-2017.06，中国海洋大学，海洋生物学，硕士
2017.09-2021.06，中国海洋大学，遗传学，博士
2021.07-2024.02，中国海洋大学海洋生命学院，博士后
2024.02至今，中国海洋大学海洋生命学院，“青年英才工程第三层次”，副教授
主要研究领域及成果
致力于海洋贝类遗传育种研究，聚焦贝类经济性状遗传机制解析与育种应用。利用遗传学、分子生物学、细胞生物学和功能基因组学等技术，揭示海洋贝类重要经济性状的遗传基础及调控机理，为高产、优质贝类良种的选育提供理论支撑和技术支持。近年来以首作者/通讯作者（含共同）发表SCI论文10余篇，主持承担了国家自然科学基金青年基金、山东省自然科学基金青年基金、国家重点研发计划项目子课题、青岛市博士后应用研究项目等课题项目，参与国家和省部级项目6项。参与培育优质高产栉孔扇贝新品种“蓬莱红3号”，产业效益显著。
代表性文章（#共同第一；*通讯作者）
1) Yihan Zhang#, Huizhen Wang#, Shiqi Liu, Xiangfu Kong, Lirong Chang, Liang Zhao, Zhenmin Bao, Xiaoli Hu*. Multi-tissue metabolomic profiling reveals the crucial metabolites and pathways associated with scallop growth. BMC Genomics 2024, 25(1):1091.
2) Shiqi Liu#, Shuyue Wang#, Liang Zhao, Tingting Li, Yihan Zhang, Huizhen Wang*, Zhenmin Bao, Xiaoli Hu*. Functional analysis of β-carotene oxygenase 2 (BCO2) gene in Yesso scallop (Patinopecten yessoensis). International Journal of Molecular Sciences 2024, 25(7):3947.
3) Xiangchao Zhang#, Xiaogang Xun#, Deting Meng, Moli Li, Lirong Chang, Jiaoxia Shi, Wei Ding, Yue Sun, Huizhen Wang*, Zhenmin Bao, Xiaoli Hu*. Transcriptome analysis reveals the genes involved in oxidative stress responses of scallop to PST-producing algae and a candidate biomarker for PST monitoring. Antioxidants 2023, 12(6):1150.
4) Tingting Li#, Yihan Zhang#, Shiqi Liu, Moli Li, Ruixing Yao, Senyu Niu, Jingyao Yuan, Huizhen Wang*, Jingjie Hu, Zhenmin Bao, Xiaoli Hu*. Transcriptome and network analyses reveal key pathways and genes involved in response to carotenoid deposition in scallop muscle. Frontiers in Marine Science 2023, 10:1158325.
5) Yujue Wang#, Moli Li#, Jiarun Lou, Xiaogang Xun, Lirong Chang, Yangrui Wang, Quanqi Zhang, Longfei Lu, Huizhen Wang*, Jingjie Hu, Zhenmin Bao, Xiaoli Hu*. Transcriptome and network analyses reveal the gene set involved in PST accumulation and responses to toxic Alexandriumminutum exposure in the gills of Chlamys farreri.International Journal of Molecular Sciences 2022, 23(14):7912.
6) Moli Li, Yangrui Wang, Zhihong Tang, Huizhen Wang*, Jingjie Hu, Zhenmin Bao, Xiaoli Hu. Expression plasticity of peroxisomal acyl-coenzyme A oxidase genes implies their involvement in redox regulation in scallops exposed to PST-producing Alexandrium. Marine Drugs 2022, 20(8):472.
7) Shuyue Wang#, Huizhen Wang#, Liang Zhao#, Yihan Zhang, Tingting Li, Shiqi Liu, Jiaoxia Shi, Shanshan Lian, Jingjie Hu, Zhenmin Bao, Xiaoli Hu*. Identification of genes associated with carotenoids accumulation in scallop (Patinopecten yessoensis). Aquaculture2022, 550:737850.
8) Huizhen Wang, Shiqi Liu, Xiaogang Xun, Moli Li, Jiarun Lou, Yihan Zhang, Jiaoxia Shi, Jingjie Hu, Zhenmin Bao, Xiaoli Hu*. Toxin- and species-dependent regulation of ATP-binding cassette (ABC) transporters in scallops after exposure to paralytic shellfish toxin-producing dinoflagellates. Aquatic Toxicology 2021, 230:105697.
