朱延平,博士,副教授,硕士生导师
邮箱:zhuyanping1123@ouc.edu.cn
电话:0532-85905527
学习工作经历:
2011.09~2015.07,哈尔滨工业大学,学士,生物工程专业
2015.09~2018.06,山东大学,硕士, 微生物学专业
2018.09~2022.06,山东大学,博士, 微生物学专业
2022.06~2022.10,青岛大学生命科学学院,讲师(青年卓越人才岗)
2022.10~2025.01,山东大学微生物技术国家重点实验室,重点资助类博士后
2025.01~至今,中国海洋大学海洋生命学院,“青年英才工程”第三层次副教授
主要科研领域:
主要从事海洋细菌分子遗传及生理代谢的相关工作。包括:1、建立和优化海洋细菌遗传操作技术;2、对海洋细菌的生理与代谢途径定向改造;3、构建具有海洋特色的合成生物学底盘细胞等。
以第一/通讯作者身份在国内外主流刊物发表论文二十余篇。代表性成果发表在Molecular Microbiology、Environmental Microbiology、Microbial Biotechnology、Applied and Environmental Microbiology等微生物领域权威期刊上。主持承担了国家自然科学基金青年项目、江苏省基础研究计划、中国博士后基金面上项目、山东省自然科学基金青年项目、青岛市自然科学基金青年项目、青岛市应用研究项目等项目/课题。
代表性成果(#共同第一;*通讯作者):
1. Yanping Zhu*, Hanlei Zhang, Meng Liu, Xiuhua Pang*. Impact of the alkaline volatile trimethylamine on the physiology of Streptomyces venezuelae: an integrated transcriptomic and metabolomics study. Microbiology Spectrum, 2025, 13(7):e00318-25.
2. Yanping Zhu, Hanlei Zhang, Xiuhua Pang*. Metabolomic analysis of the impact of MtrA on carbon metabolism in Streptomyces coelicolor. Microbiology Spectrum, 2025, 13(8): e00096-25.
3. Yanping Zhu, Yanhong Zeng, Meng Liu, Ting Lu, Xiuhua Pang*. Rescue of morphological defects in Streptomyces venezuelae by the alkaline volatile compound trimethylamine. Microbiology Spectrum, 2024, 12(9): e01195-24.
4. Yanping Zhu, Xinyuan Wang, Jing Zhang, Xue Ni, Xia Zhang, Meifeng Tao, Xiuhua Pang*. The regulatory gene wblA is a target of the orphan response regulator OrrA in Streptomyces coelicolor. Environmental Microbiology, 2022, 24(7):3081-3096.
5. Ting Lu#, Yanping Zhu#, Xue Ni, Xia Zhang, Yang Liu, Xiqing Cui*, Xiuhua Pang*. Mutation of MtrA at the predicted phosphorylation site abrogates its role as a global regulator in Streptomyces venezuelae. Microbiology Spectrum, 2022, 10(2): e02131-21.
6. Yanping Zhu, Jiao Wang, Wenya Su, Ting Lu, Aiying Li, Xiuhua Pang*. Effects of dual deletion of glnR and mtrA on expression of nitrogen metabolism genes in Streptomyces venezuelae. Microbial Biotechnology, 2022, 15(6): 1795-1810.
7. Yanping Zhu, Peipei Zhang, Ting Lu, Xinyuan Wang, Aiying Li*, Yinhua Lu, Meifeng Tao, Xiuhua Pang*. Impact of MtrA on phosphate metabolism genes and the response to altered phosphate conditions in Streptomyces. Environmental Microbiology, 2021, 23(11):6907-6923.
8. Yanping Zhu, Peipei Zhang, Jing Zhang, Jiao Wang, Yinhua Lu, Xiuhua Pang*. Impact on multiple antibiotic pathways reveals MtrA as a master regulator of antibiotic production in Streptomyces spp. and potentially in other actinobacteria. Applied and Environmental Microbiology, 2020, 86(20): e01201-20.
9. Yanping Zhu, Wenhao Xu, Jing Zhang, Peipei Zhang, Zhilong Zhao, Duohong Sheng, Wei Ma, Yu-Zhong Zhang, Linquan Bai, Xiuhua Pang*. A hierarchical network of four regulatory genes controlling production of the polyene antibiotic FR008/candicidin in Streptomyces sp.FR008. Applied and Environmental Microbiology, 2020, 86(9):e00055-20.
10. Yanping Zhu#, Ting Lu#, Jing Zhang, Peipei Zhang, Meifeng Tao, Xiuhua Pang*. A novel XRE family regulator that controls antibiotic production and development in Streptomyces coelicolor. Applied Microbiology and Biotechnology, 2020, 104(23):10075-10089.
11. Yanping Zhu#, Peipei Zhang#, Jing Zhang, Wenhao Xu, Xinyuan Wang, Lili Wu, Duohong Sheng, Wei Ma, Guangxiang Cao, Xiu-lan Chen, Yinhua Lu, Yu-Zhong Zhang, Xiuhua Pang. The developmental regulator MtrA binds GlnR boxes and represses nitrogen metabolism genes in Streptomyces coelicolor. Molecular Microbiology, 2019, 112(1):29-46.